With the sequencing of the human genome and the genomes of other organisms, we now have a list of the parts that make up these genetic systems. Using this information, researchers are now able to engineer synthetic genetic circuits for a range of applications in the environmental, medical, and energy domains. Crucial to these efforts' success is the development of methods and tools for designing these genetic circuits. While inspiration can be drawn from experiences with electronic design, design with a genetic material poses several challenges. Genetic circuits are composed of very noisy components making their behavior more asynchronous, analog, and stochastic in nature. This specialization presents recent research into new methods and software tools for the modeling, analysis, and design of genetic circuits that are enabling this exciting new field of synthetic biology. As in the sequencing of the human genome, collaborations between engineers and biologists will be essential to the success of synthetic biology. Therefore, the goal of this specialization is to facilitate these collaborations by teaching both the biological and engineering principles necessary for such research.
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Engineering Genetic Circuits Specialization
Design Genetic Circuits for Synthetic Biology. Gain the skills to design, model, analyze, and construct genetic circuits used in synthetic biology.
Instructors: Chris Myers
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What you'll learn
Design genetic circuits using genetic parts and devices .
Create and analyze a model of a genetic circuit to understand its behavior.
Evaluate advantages and disadvantages of different abstraction methods for genetic analysis and design.
Overview
Skills you'll gain
- Mathematical Modeling
- Computational Logic
- Molecular Biology
- Engineering Analysis
- Biochemistry
- Molecular, Cellular, and Microbiology
- Chemical and Biomedical Engineering
- Software Visualization
- Bioinformatics
- Differential Equations
- Simulations
- Electrical and Computer Engineering
- Markov Model
- Computational Thinking
- Simulation and Simulation Software
- Failure Analysis
- Engineering Design Process
- Systems Design
- Electrical Engineering
- Systems Analysis
What’s included
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Advance your subject-matter expertise
- Learn in-demand skills from university and industry experts
- Master a subject or tool with hands-on projects
- Develop a deep understanding of key concepts
- Earn a career certificate from University of Colorado Boulder
Specialization - 3 course series
What you'll learn
Identify the different types of cells, their components, and structure.
Discover the underlying structure of devices and their connection to genetic parts.
Contrast different experimental techniques used in genetic construction.
Evaluate the different principles used in genetic circuit design.
Skills you'll gain
What you'll learn
Design and analyze models of genetic circuits.
Simulate genetic circuit models using ODE simulation methods.
Simulate genetic circuit models using stochastic simulation methods.
Utilize genetic technology mappers to select parts for genetic designs.
Skills you'll gain
What you'll learn
Derive abstracted reaction-based models of genetic circuits.
Utilize piecewise models of genetic circuits.
Perform analysis of Markov chain models.
Construct state-based abstracted models of genetic circuits.
Skills you'll gain
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Build toward a degree
This Specialization is part of the following degree program(s) offered by University of Colorado Boulder. If you are admitted and enroll, your completed coursework may count toward your degree learning and your progress can transfer with you.¹
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Frequently asked questions
This specialization will take about 3 months to complete.
A basic understanding of biology and/or engineering principles is recommended.
It is recommended to complete the courses in this Specialization sequentially.
More questions
Financial aid available,